| 研究成果： |
1. Rui Hua, Xiaoyu Jiang, Lingxia Qi, Shanshan Guan, Ziyu Kuai, Yongbo Qiao, Yan Xu, Xin Gong, Yuhua Shi, Wei Kong, Junqi Niu, Hao Zhang, Yaming Shan. Screening HCV genotype-specific epitope peptides based on conserved sequence analysis and B cell epitope prediction in HCV E2 region. Immunologic Research, 2018, 66(1): 67-73.
2. Shanshan Guan, Yan Xu, Yongbo Qiao, Ziyu Kuai, Mengdan Qian, Xiaoyu Jiang, Song Wang, Hao Zhang, Wei Kong & Yaming Shan. A novel small molecule displays two different binding modes during inhibiting H1N1 influenza A virus neuraminidases. Journal of Structural Biology, 2018, 202(2):142-149.
3. Yusha Feng，Ziyu Kuai，Yan Song，Jing Guo，Qingbiao Yang，Yaming Shan,
Yaoxian Li. A novel "turn-on" thiooxofluorescein-based colorimetric and
fluorescent sensor for Hg2+ and its application in living cells. Talanta, 2017,
170: 103-110.
4. Zhandong Li, Ketong Zhu, Xin Gong, Steven Vasilescu, Yu Sun, Kaiqing Hong, Hao Li, Lin Li, Yaming Shan. Inducing Polyclonal Eag1-Specific Antibodies by Vaccination with a Linear Epitope Immunogen and Its Relation to Breast Tumorigenesis. Pathology & Oncology Research, 2017, 23(4): 761-767.
5. Yongjiao Yu, Lu Fu,Xin Gong, Shanshan Guan, Xiaoqiu He, He Yin, Ziyu Kuai, Wei Kong, Yuhua Shi, Yaming Shan. Eliciting 10E8-like antibodies by the membrane proximal external region peptide of HIV-1 in guinea pigs. Biotechnology Letters, 2017, 39(3): 367-373.
6. Shanshan Guan, Li Zhao, Hanyong Jin, Ning Shan, Weiwei Han, Song Wang &Yaming Shan. Binding modes of phosphotriesterase-like lactonase complexed with δ-nonanoic lactone and paraoxon using molecular dynamics simulations. Journal of Biomolecular Structure and Dynamics, 2017, Vol. 35, No. 2, 273-286,
7. Shanshan Guan, Tianao Wang, Ziyu Kuai, Mengdan Qian, Xiaopian Tian, Xiuqi Zhang, YongjiaoYu, Song Wang, Hao Zhang, Hao Li, Wei Kong & Yaming Shan. Exploration of binding and inhibition mechanism of a small molecule inhibitor of influenza virus H1N1 hemagglutinin by molecular dynamics simulation. Scientific Reports, 2017, 7:3786.
8. Xun Sun, Mengdan Qian, Shanshan Guan, Yaming Shan, Ying Dong, Hao Zhang, Song Wang, and Weiwei Han. Investigation of an "alternate water supply system" in enzymatic hydrolysis in the processive endocellulase Cel7A from Rasamsonia emersonii by molecular dynamics simulation. Biopolymers, 2017, 107: 46-60.
9. Mengdan Qian, Shanshan Guan, Yaming Shan, Hao Zhang, Song Wang, Structural and molecular basis of cellulase Cel48F by computational modeling: Insight into catalytic and product release mechanism. Journal of Structural Biology, 2016, 194: 347-356.
10. Yongjiao Yu, Lu Fu, Xiaoyu Jiang, Shanshan Guan, Ziyu Kuai, Wei Kong, Yuhua Shi, Yaming Shan Expression of HIV-1 broadly neutralizing antibodies mediated by recombinant adeno-associated virus 8 in vitro and in vivo. Molecular Immunology. 2016, 80:68-77.
11. Xin Gong, He Yin, Yuhua Shi, Shanshan Guan, Xiaoqiu He, Lan Yang, Yongjiao Yu, Ziyu Kuai, Chunlai Jiang, Wei Kong, Song Wang, Yaming Shan. Conserved stem fragment from H3 influenza hemagglutinin elicits cross-clade neutralizing antibodies through stalk-targeted blocking of conformational change during membrane fusion. Immunology Letters, 2016, 172: 11-20.
12. Ziyu Kuai,Yan Xu,Qi Zhao,Jie Liu, Shanshan Guan, Yongbo Qiao, Xin Gong, Jiaojiao Nie, Pengju Li, Dongni Liu, Yifan Xing, Huiwen Li, Zixiao Sun, Wenqi Wang, Chunan Ning, Yuhua Shi, Wei Kong, Yaming Shan. Effects of insulin on transcriptional response and permeability in an in vitro model of human blood-brain barrier. DOI:10.1002/jcb.26744
13. Xiaoqiu He, Huayan Zhang, Yuhua Shi, Xin Gong, Shanshan Guan, He Yin, Lan Yang, Yongjiao Yu, Ziyu Kuai, Dongni Liu, Rui Hua, Song Wang, Yaming Shan. A novel antimicrobial peptide derived from membrane-proximal external region of human immunodeficiency virus type 1. Biochimie, 2016, 123: 110-116.
14. Huayan Zhang, Xiaoqiu He, Yuhua Shi, Yongjiao Yu, Shanshan Guan, Xin Gong, He Yin, Ziyu Kuai and Yaming Shan. Potential of a novel peptide P16-D from the membrane-proximal external region of human immunodeficiency virus type 1 to enhance retrovirus infection. RSC Advances, 2016, 6(85): 82082-82087.
15. Xin Gong, He Yin, Yuhua Shi, Xiaoqiu He, Yongjiao Yu, Shanshan Guan, Ziyu Kuai, Nasteha M Haji, Nafisa M Haji, Wei Kong and Yaming Shan. Evaluation of immunogenicity and protective effects of a trivalent chimeric Norovirus P particle immunogen displaying influenza HA2 of H1, H3 and B subtypes. Emerging Microbes and Infections, 2016, 5, e51.
16. Xiaoyu Jiang, Shanshan Guan, Yongbo Qiao, Xiao Li, Yan Xu, Lan Yang, Ziyu Kuai, Haihong Zhang, Yuhua Shi, Wei Kong, Yaming Shan, Hao Zhang. Effects of poly(I:C) and MF59 co-adjuvants on immunogenicity and efficacy of surviving polypeptide immunogen against melanoma. Journal of cellular physiology, 2018, 233(6): 4926-4934.
17. 王嵩，管珊珊，万永凤，单亚明，张浩.血管紧张素转换酶与抑制肽结合模式的分子动力学研究. 高等学校化学学报, 2017, 38(7): 1216-1222.
18. Mengdan Qian, Yaming Shan, Shanshan Guan, Hao Zhang, Song Wang, and Weiwei Han. Structural Basis of Fullerene Derivatives as Novel Potent Inhibitors of Protein Tyrosine Phosphatase 1B: Insight into the Inhibitory Mechanism through Molecular Modeling Studies. Journal of Chemical Information and Modeling, 2016, 56: 2024?2034.
19. Yongjiao Yu, Lu Fu, Yuhua Shi, Shanshan Guan, Lan Yang, Xin Gong, He Yin, Xiaoqiu He, Dongni Liu, Ziyu Kuai, Yaming Shan, Song Wang, Wei Kong. Elicitation of HIV-1 neutralizing antibodies by presentation of 4E10 and 10E8 epitopes on Norovirus P particles. Immunology Letters, 2015, 168:271-278.
20. Yang Zang, Jinpeng Bi, Dongchuan Du, Xintao Liu, Yan Zhang, Weiheng Su, Jiaxin Wu, Yaming Shan, Song Wang, Wei Kong, Aidong Qiu, Chunlai Jiang. Development of a norovirus P particle platform for eliciting neutralizing antibody responses to the membrane proximal external region of human immunodeficiency virus type 1 envelope. Protein and peptide letters, 2014, 21(12): 1230-1239.
21. Lishuang Zhang, Chunlai Jiang, Huayan Zhang, Xin Gong, Lan Yang, Liang Miao, Yuhua Shi, Yan Zhang, Wei Kong, Chuntao Zhang, Yaming Shan. A novel modified peptide derived from membrane‐proximal external region of human immunodeficiency virus type 1 envelope significantly enhances retrovirus infection. Journal of Peptide Science, 2014, 20(1): 46-54.
22. 授权发明专利：一种多肽类促感染试剂，专利号：ZL 2012 1 0336804.X，发明人：单亚明，孔维，张丽双，张浩，管珊珊。
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